Best Western On the River
401 N 3rd Street,
Hannibal, Missouri, 63401-3301,
United States
Phone: 573/248-1150
Fax: 573/248-1155

General Hotel Information:

Check In: 3PM (15:00)    
Check Out: 11AM (11:00)
Hotel Ratings: AAA-3 Diamond
Pet Policy: No pets allowed

Hotel Amenities:

  • Exercise facilities
  • Wireless internet connection in public areas
  • 100% smoke-free hotel
  • 24-hour front desk
  • Complimentary full breakfast, choice of breads, cereal, fruit, hot eggs, hot breakfast meat, other hot items, yogurt, juice and coffee.
  • Indoor pool
  • Hot tub

Guest Room Amenities:

  • Cable or satellite television, CNN or other 24 hour news station
  • AM/FM alarm clock
  • AM/FM radio stereo
  • Coffee/tea maker
  • Microwave
  • Refrigerator
  • Hairdryer

Area Information:

  • 0.10 mile(s) from Twainland Express Sightseeing
  • 0.10 mile(s) from The Mark Twain House & Museum
  • 0.10 mile(s) from Planters Barn Theater, Mark Twain himself shows
  • 0.10 mile(s) from Hannibal Trolley Company, sightseeing tours
  • 0.10 mile(s) from Tom & Huck Statue
  • 0.10 mile(s) from Mark Twain Lighthouse
  • 0.20 mile(s) from Spratt Theater, dinner and show


  • 104 mile(s) from Lambert-St Louis International Airport
  • 212 mile(s) from Kansas City International Airport
  • 297 mile(s) from Chicago Midway International Airport
  • 20 mile(s) from Amtrak


  • 2 mile(s) from Hannibal-LaGrange College
  • 3 mile(s) from Moberly Area Community College, Hannibal campus
  • 20 mile(s) from Quincy University
  • 20 mile(s) from John Wood Community College
  • 20 mile(s) from Vatterott College
  • 20 mile(s) from Blessing Rieman College of Nursing
  • 30 mile(s) from Culver-Stockton College


  • From: Lambert Airport, St. Louis Take Interstate 70 West to Highway 61 North. Turn right on Interstate 72 East and take Exit 157, turn right, Mark Twain Avenue runs into Highway 79. The Best Western On The River is located on the right.

  • From: Quincy Airport. Take Interstate 72 West/US-36 West, take the MO-79/US 36-BR Exit, take Exit 157 toward Louisiana/downtown Hannibal. Turn left onto US-36 BR/US-61 BR/MO-79. The Best Western On The River is located on the right.

  • From: Burlington, IA. Take US-61 South toward Hannibal. Merge onto Interstate 72 East/US-36 East/US-61 BR South/Mark Twain Avenue via the ramp on the left toward Springfield, IL. Take the US-36-BR/US-61 BR/MO-79 South Exit, then take Exit 157 toward Louisiana. Turn slightly right onto US-36 BR/US-61 BR/Mark Twain Avenue. The Best Western On The River is located on the right.
Important: Map and directions are for information purposes only. While we hope to provide the best mapping information for Best Western hotels, some mapping details may not be as accurate as we would like. Please contact hotel directly to obtain the most current and complete location information and driving directions.


  • Across the street from Mark Twain Dinette, Full Service, American, Open for: breakfast, lunch, dinner,
  • 0.1 mile(s) from Ole Planters, Full Service, American, Open for: lunch, dinner,
  • 0.2 mile(s) from Brick Oven, Bar/Lounge, Italian, Open for: lunch, dinner,
  • 0.2 mile(s) from Breadeaux Pizza, Full Service, American, Open for: lunch, dinner,
  • 0.2 mile(s) from Lulabelles, Full Service, American, Open for: lunch, dinner,
  • 0.2 mile(s) from Jumping Frog, Deli, American, Open for: lunch,
  • 2 mile(s) from TJ's Supper Club, Full Service, American, Open for: lunch, dinner,

Corporate Locations:

  • 4.00 mile(s) from Continental Cement Company
  • 4.00 mile(s) from Altorfer Inc..
  • 5.00 mile(s) from Buckhorn Industries, rubber products
  • 5.00 mile(s) from Watlow Industries
  • 5.00 mile(s) from General Mills
  • 5.00 mile(s) from Hannibal Clinic
  • 5.00 mile(s) from James E. Cary Cancer Center


  • 0.10 mile(s) from T'S & Trivia
  • 0.10 mile(s) from Rags To Riches, pawnshop
  • 0.20 mile(s) from Native American Trading
  • 0.20 mile(s) from Ayers Pottery
  • 0.20 mile(s) from Groomingdales, pet boutique
  • 0.20 mile(s) from Hickory Stick Quilt Shop
  • 0.40 mile(s) from The Opened Book, comics, unique creations of gifts, books, incense, candles, jewelry, herbs etc.